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John Stuart wrote: "Artane is still my best defense against tremors, despite occasional side effects." John - Thank you for your thoughtful letter describing where you have been and where you are with treating your PD and particularly the tremor. You have helped me to have an open mind toward Artane. I tried Cogentin very early on (1989). It turned me into a zombie and I quit after three weeks. Just this week I have finally found a neurologist I am very happy with. I have been to five others and was not comfortable with any of them. Dr. Pierce, my present neuro, listens to me, discusses research with me and does not push in any direction. He is wonderful!--and the end result is I am trying Requip for now. If that doesn't work I will consider trying Artane. He explained that even though Artane and Cogentin are both acetylcholine inhibitors, they are chemically quite different from each other. Anyway--thanks, John. I appreciate your thoughtfulness and I appreciate your help. Sincerely, Joan Dykstra