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Hello, Leanne and Michael - Your father/FIL's symptoms sound a lot like my mother's at one point. She was hospitalized for one month and received three (unilateral, if I remember correctly) ECT treatments per week. The doctor warned us that she would need regular follow-up and, sure enough, when we/he/nursing home let it slide, she got worse again. We found that a minimum of once monthly was necessary. I'd seen literature that said follow-up with clozarine(Clorazil) is also imperative. In the meantime, olanzapine (zyprexa) had gone on the market (generally fewer side effects than clorazil), so that's what Mom took. She'd been on a variety of antidepressants of the prozac type as well. Temporarily, the ECT helped Mom both physically and emotionally. But she was already 75 when the treatments started, and her pd had progressed rapidly, and all the negative-thinking and passive aspects of her personality had blossomed over the last couple of years. Being younger, your father has a much better chance, I think, of benefiting from meds and/or ECT. Is his neurologist working with the psychiatrists? We found it VITAL that they cooperate and insisted upon it, althought the shrink had his nose put out of joint when the neuro's nurse-clinician called him! If you tell us more about your father's current meds and maybe past meds' history, you will probably get more specific instructions. My thoughts will be with you; this is definitely the worst aspect of the disease, as far as I am concerned ... Mary Rack