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Shari asked: "Hello Joan... Would you explain what "chelation" is. I've seen bumper stickers on cars saying "I support chelation"....but personally I have no idea what it is. Thanks very much. Cheers, Shari" Shari - Chelation usually refers to chelation therapy using EDTA (ethylene diamine tetraacetic acid). The word chelation refers to the way certain synthetic chemical and body proteins can bind metal molecules. EDTA has extra negative charges that can combine with positive ones of metals and thus remove it from the body. IV infusions with EDTA is the established method used around the world for removal of heavy metals. While there are no double blind studies testing the use of chelation therapy to improve circulation (probably its most common use), there is a great deal of evidence in the form of anicdotal records that it has in many cases turned around problems with atherosclerosis. Because many diseases have a circulation component, it has been helpful for many other diseases as well. We may never see the double blind studies for chelation because the patent for EDTA ran out in 1948. The ACAM (American College of Advancement in Medicine) has drawn up guidelines and set up training for doctors for the safe and effective use of EDTA. They have a certification process for doctors, and it is important that the doctor you choose is following their guidelines.