Direct from the UCLA Web page - Information about their collagen injections procedure to aid those Parkies having weak voices. The phone number listed on the site is (310) 825-2023. I've found ya usually get voice mail unless ya call close to 5 p.m. PST at this number as it's Dr. Burke's nurse's phone - She's ALWAYS busy! The Head & Neck Clinic's lobby phone number's (310) 206-6688. Barb Mallut (who has had this beneficial procedure) [log in to unmask] ----------------------------------------------------- Many people with neurologic disorders such as Parkinson's disease develop weak, breathy voices that are not loud enough to be heard or understood. Efforts to overcome this weakness by talking loudly or shouting may lead to rapid fatigue in the speaker. Patients who lose the use of their voice may feel they have lost their identity. They often have difficulty talking on the telephone or performing a job. Such patients can become isolated as they are forced to withdraw from work and society. Vocal weakness in patients with neuromuscular disorders (including Parkinson's disease) usually occurs because the two vocal folds (also called the vocal cords) do not meet completely during the vibration that produces sound. Often the vocal folds of these patients demonstrate a bowed appearance. When the vocal folds do not close tightly during speech, efficient voice production cannot occur. Augmentation of the vocal folds with collagen can successfully restore the voice to a more normal loudness level, by helping the vocal folds close more completely during vibration. Until recently, people with Parkinson's disease were poor candidates for voice augmentation, because prevailing techniques required general anesthesia or open surgical operations, which are risky for such patients. A new approach has been pioneered by Dr. Gerald S. Berke of the Division of Head and Neck Surgery at UCLA. In this new procedure, collagen is injected through the neck into the vocal folds. This augmentation procedure is performed on an outpatient basis, and does not require general anesthesia. How the Procedure Works Patients are first assessed in the UCLA Center for Voice in Medicine and the Arts to determine their candidacy for the procedure. During this assessment, the patient's larynx is visualized with a stroboscope, a sample of voice and speech is recorded, and aspects of laryngeal air flow and pressure are studied. Those who are most helped by this procedure have a weak voice resulting primarily from incomplete vocal fold closure during vibration, but can pronounce words clearly and are not hard to understand. Patients who are good candidates for the procedure are given a test dose of collagen to screen for sensitivity. About four weeks after the initial screening, the procedure is performed in the doctor's office. It takes about 15 minutes to complete. First, the nurse sprays a local anesthetic in the nostril to reduce any possible irritation. No other anesthetic is required. A thin flexible tube is then inserted through the nose to see down the throat. The doctor now injects a small amount of collagen through the front of the neck and into the vocal folds. The injection is guided by pictures of the vocal folds on a video monitor, and is made with a small syringe like the ones used to administer a flu shot. The injected collagen gently pushes the vocal cords toward each other to correct for the bowing and produce a stronger voice. This procedure is very well tolerated, and has been successfully performed on adolescent and geriatric patients. Normally, a patient can leave the clinic immediately after the procedure and drive a car if desired. Results are noticed within one to two days. The effects of the procedure, which uses bovine collagen, last for about three to six months. The procedure may be repeated if necessary. Autogenous collagen may also be harvested from the patients themselves. This collagen may last longer. To date, Dr. Berke has performed this procedure more than 250 times. No medical complications of the procedure have been noted to date. Most patients have achieved excellent results, although patients with prominent vocal tremors have had more variable results than patients without vocal tremors. #