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Kathy Barras wrote: > > Is it ok to chew Sinemet (not Sinement CR)?? > > Kathy Barras (cg for mom, Florence, 73/Sept 97) Chewing an entire tablet of either does not make much sense. The regular will dissolve relatively rapidly. It is not uncommon to dissolve a tablet in ginger ale or orange juice with added ascorbic acid (vit C) and drink a portion to get rapid transit into the lower stomach and into the small intestine to be absorbed quickly. This will not "work" if the stomach is not relatively empty. chewing the CR will defeat the "controlled release" - slow dissolving "binder" comprising the tablet. smaller pieces of either will tend to dissolve faster. The digestive acids and presence of minimum amount of food to cause digestive flow into the duodenum is requisite for the levodopa and carbidopa to get into the blood stream through the intestinal wall via the LNAA-tranporters as I recall they are labeled. -- Ron Vetter 1936, '84 PD dz paradise is feeling good, not a place to go [log in to unmask] http://www.ridgecrest.ca.us/~rfvetter