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I just wanted to report that my mother Joyce (68/1 year) has been feeling better for about 6 days in a row now. This is a record since she went off all PD drugs in October. Currently, she's on Requip and a very low dose of Sinemet. But it wasn't until she added the Paxil that the benefits came -- mostly the tightness in her chest is better. What is interesting to me is that she did not start the Paxil because of any symptoms that you could define as "depression." She had been put on Paxil in July, around the time that my father ended up in a heart hospital and her doctor thought that she might benefit from the Paxil. The effects were clear then. However, for whatever reason, she began to experience a very discomforting tightness in her chest (which I've written about here). She went off all drugs at the time in an effort to try to pinpoint what was causing the tightness. (Her doctor took her off the Paxil, too, so that she could try Eldelpryl.) Then she and her doctor decided to try Requip and then she recently added some Sinemet. But none of this helped with the tightness that was so distressing. I believe it's the Paxil that did that. I will never underestimate the value of a drug like Paxil. And I just wanted others to know that such drugs seem to benefit even those without obvious signs of depression. Debbie White [log in to unmask]