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Hi gang; This morning after rereading all the recent posts on carbidopa/levadopa and the different meds we employ and different response times we experience I remembered a recent Group Support discussion on the same theme. In reference to early morning meds (on rising) some use liquid sinemet, others a non-CR tablet to give them a quick response (as opposed to taking a Sinemet CR tablet and waiting 1 to 1 and 1/2 hours for meds to be at optimum). One person suggested a quick response could also be obtained by simply chewing 1/2 a Sinemet CR tablet followed by a glass of orange juice. I have tried this and it seems to work very well for me and then I only need to have one Sinemet prescription. (Just the 50/200 Sinemet CR) What do you think????? Best regards............Murray . [log in to unmask]