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    As  a  supplement  to  the  journal _Neurology_ 1998;50(Suppl
3):Sl, C. Warren  Olanow, MD, FRCPC,  and William C.  Koller, MD,
PhD wrote  "An algorithm  (decision tree)  for the  management of
Parkinson's disease:  Treatment guidelines."

    It is one of the best  and up to the minute accounts  of what
is happening in PD.  I wish I could reproduce the entire 50  some
odd pages here for everyone to read but the copyright laws  would
prohibit  that.    Here,  below,  is  a short exerpt dealing with
exercise    and    diet    under    the   supplement's   heading,
NONPHARMACOLOGIC TREATMENTS



    Exercise.  Exercise is an important adjunctive therapy for PD
and can  be one  of the  most beneficial  activities in which the
patient is  involved (breakout  2).10 Although  exercise has  not
been shown  to have  direct effects  on the  cardinal symptoms of
bradykinesia, tremor, postural  instability, or rigidity,  it can
slow the secondary effects  of these problems that  further limit
mobility and functional activity. 11,12

    ***  ***  [The  chart  Breakout  2  should  go  here with the
following caption:]  Breakout 2.  Although exercise  has not been
shown to directly change the cardinal symptoms of PD, a  regular,
focused exercise program that includes aerobics, stretching,  and
strengthening activities  can have  positive effects  on mobility
and mood.

    Patients should  be educated  about the  positive effects  of
exercise  on  mobility  and  mood.    An  exercise program should
include aerobic, strengthening,  and stretching activities.   One
does not replace the other.  Aerobic exercise should be done at a
training heart rate of 60 to 70% maximal heart rate.   Stretching
should be done when muscles are warm, and strengthening should be
done with light weights.

    The goal should  be to improve  flexibility and strength  but
not bulk.  The emphasis should be placed on the extensor  muscles
to counteract the flexor postures that tend to develop in PD.   A
reasonable  goal  is  to  work  up to 20-minute exercise sessions
three times a week.

    Patients who are  interested in an  exercise program but  are
not sure  how to  get started  should be  referred to  a physical
therapist or a PD exercise group.  Before an exercise program  is
started, other potentially complicating medical problems, such as
heart  disease,  should  be  ruled  out.    The baseline level of
fitness can be determined by measuring maximal heart rate.  Other
limitations  of  mobility,  such  as  decreased  range of motion,
should   be   identified   to   minimize   the  risk  of  injury.
Non-weight-bearing  exercise  (e.g.,   water  aerobics)  may   be
particularly beneficial for a PD patient.

    *** *** [The chart Breakout 3 goes here and has the following
caption:]  Breakout  3.  Establishment  and  maintenance  of good
nutritional habits are integral components of the manage ment  of
PD.    Clinicians  should  obtain  a thorough dietary history and
identify current eating habits.  It is essential to help patients
become aware of  their dietary habits  and to educate  them about
the  elements  of  a  balanced  diet  and  about  techniques  for
successfully altering poor eating habits.  Nutritional counseling
may be beneficial in some patients.

    Nutrition.  Patients with PD  are at increased risk for  poor
nutrition, weight loss, and reduced muscle mass in comparison  to
healthy controls.13,14 Good nutrition is essential to the overall
well-being of patients with  both early- and late-stage  disease.
Although  no  specific  diet  is  required, patients should eat a
balanced diet that contains sufficient fiber and fluid to prevent
constipation  and  enough  calcium  to  maintain  existing   bone
structure.   Although patients  often ask  about dietary  protein
restriction, this  is usually  a concern  only for  patients with
late-stage disease, in which amino-acid competition for  levodopa
absorption causes erratic responses to levodopa therapy.15

    It is important to establish and maintain good eating  habits
in patients with early PD (breakout 3).  Clinicians should obtain
a thorough  dietary history  and identify  current eating habits.
This  is  an  opportunity  to  identify  those  patients  who are
following  nontraditional  diets  that  may  be harmful.  Helping
patients become aware of their dietary habits and educating  them
about  the  elements  of  a  balanced  diet and the techniques to
successfully alter poor eating  habits is essential.   Increasing
the quantity of fiber and  fluids in the newly diagnosed  patient
is useful and may prevent  or minimize constipation later in  the
course  of  the  disease.  16  In  some  instances,   nutritional
counseling with a clinical dietitian may be of value.

    Patients who have difficulty maintaining a balanced diet  may
be  candidates  for  a  supplemental  multiple  vitamin,  with or
without  calcium  supplementation.    A  large body of literature
supports a role of oxidative stress in the pathophysiology of  PD
.17-21   However,   at   present   there   is  no  evidence  that
supraphysiologic or megadoses of antioxidants (e.g., a-tocopherol
or vitamin  E) alter  the course  of the  disease '22-24 and such
treatments may be very  costly.  On the  other hand, there is  no
current information suggesting that these agents are harmful.

[The numbers within the above text from 1 thru 24 represent footnotes
which I have not reproduced here.]

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  Sid Roberts   68/dx3
  [log in to unmask]       Youngstown, Ohio