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On Thu 09 Apr, HEIT BILL wrote: > In a message dated 98-04-08 21:06:29 EDT, you write: > > << > Meanwhile, Re: your query on increasing Carbidopa, I would say that the only > circumstance where it might be worth trying is if your current intake is less > than 100 mg per day of Carbidopa. The accepted figure is 70 mg/day;- more > than > that would not be effective in saving levadopa, because there is no more to > be saved. > On the other hand, the upper level of Carbidopa is not critical : I would > expect that most of you folk are currently taking nearer to 200 mg than 100 > mg of Carbidopa, and it isn't doing you any harm, so if you want to > experiment > there is minimal risk. The first symptoms of too much should be a noticeable > lack of 'Get-Up-and-Go !,and a general malaise. > Good luck. >> > > > i may be wrong but I have believed for years-- I think I got it from Dr Delong > ( the palli expert from Emory) that one can benefoirt from 150 mg a day and > that anything over 300 mg a day is toxic. At any rate, corbidopa is not a > totally benign drug. > Regards, > WHH > Hello Bill, I certainly agree with you that 300 mg per day is a sensible top limit for Carbidopa, although I do know people who take more without obvious harm. At the other end of the scale, I have seen 70 mg per day quoted by several sources; perhaps your Dr Delong is just being cautious? Regards, -- Brian Collins <[log in to unmask]>