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I have an appointment on Monday afternoon with a real movement disorders specialist my neuro has encouraged me to see. My main symptoms are causing me more and more problems and I am going to bring up the topic of changing medications. I currently take one 25/100 Sinement and four .25mg Permax 4 times a day (although I skip the evening ones about 1/3 the time). I have no tremor or diskenesia,. My greatest problem is bradykensia, balance, just walking in general, rigidity you might call it. It's getting worse. When the meds have worn off I literally have to bounce off the walls to get around the house. I have fallen a number of times and have messed up both my knees. I am also finding my hands are getting heavier when typing, makng that more difficult. My question is - would any of these three new drugs be likely to help these problems? Or are hey memore likely to help other symptoms like tremor. I tried for a week taking half the dosage of the Permax and Sinement twice as often, but it seemed to make my mobility worse. I have never tried Sinement CR, and I ha been taking Amantadine 200mg/day and Eldepryil 10mg/day for the past 3 years but stopped taking them about 6 weeks ago. I wold like to have some idea of what to expect from him in the way of med changes, if any. Thanks for any help anyone would care to offer. Bruce Anderson (52,3+) Schooleys Mtn, NJ [log in to unmask]