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>From: Bruce Anderson <[log in to unmask]> >I have an appointment on Monday afternoon with a real movement disorders >specialist my neuro has encouraged me to see. My main symptoms are causing >me more and more problems and I am going to bring up the topic of changing >medications. I currently take one 25/100 Sinement and four .25mg Permax 4 >times a day (although I skip the evening ones about 1/3 the time). I have no >tremor or diskenesia,. My greatest problem is bradykensia, balance, just >walking in general, rigidity you might call it. It's getting worse. When >the meds have worn off I literally have to bounce off the walls to get >around the house. this indicates that more duration from adding tolcapone - or a 5th 25/100 Sinemet so that you would be taking it just before the last one's effect is insufficient - would be recommended I have fallen a number of times and have messed up both >my knees. > >I am also finding my hands are getting heavier when typing, makng that more >difficult. > >My question is - would any of these three new drugs be likely to help >these problems? Or are hey memore likely to help other symptoms like >tremor. I would judge that you are undermedicated to the extent that you are apparently running 'out' before the next is taken. Ronald Vetter 1936, dz PD 1984, carbidopa/levodopa, Mirapex, selegiline [log in to unmask] Ridgecrest, California http://www.ridgecrest.ca.us/~rfvetter ---------- > >I tried for a week taking half the dosage of the Permax and Sinement twice >as often, but it seemed to make my mobility worse. I have never tried >Sinement CR, and I ha been taking Amantadine 200mg/day and Eldepryil >10mg/day for the past 3 years but stopped taking them about 6 weeks ago. > >I wold like to have some idea of what to expect from him in the way of med >changes, if any. > >Thanks for any help anyone would care to offer. > >Bruce Anderson (52,3+) >Schooleys Mtn, NJ >[log in to unmask] >