Janet-- Add Peter to the list of those who have taken generic Sinemet for years without any problem. Not even nausea--- His drug reactions occured because the Sinemet was not reduced when he started Mirapex, not because it was generic ("carbodopa-levodopa), which he had already been on for ages. Look at other factors, as has been suggested by folks already! Camilla Flintermann, CG for Peter 79/8 Oxford, OH [log in to unmask] * * * * * * * * * * * * * * * * * * Ask me about the CARE list for* * Parkinson's caregivers ! * * * * * * * * * * * * * * * * * *