In a message dated 4/30/98 12:40:40 AM Central Daylight Time, [log in to unmask] writes: << For any of you successfully taking Mirapex, would you please tell me what the ultimate dosage, or the one that works for you, is supposed to be? I just started. Thanks! Bruce Anderson (52, 3+) Schooley's Mtn, NJ [log in to unmask] >> My medicine dosing ( it works OK--as well as expected): @0500 ENADA 2.5 mg @0600 : 1 Sinemet--25/100 1 Amantadine 100 mg 1 Selegiline 5 mg 1/2 one mg tablet Mirapex (= 0.5 mg) 0900 75-80 % of a Sinemet 25/100 1/2 of a one mg Mirapex (still = 0.5 mg) 1100 75-80 % of a Sinemet 25/100 1/2 of a one mg Mirapex (still = 0.5 mg) 1300 75-80 % of a Sinemet 25/100 one Amantadine 100 mg capsule 1500 75-80 % of a Sinemet 25/100 3/4 of a one mg Mirapex (= 0.75 mg) 1700 75-80 % of a Sinemet 25/100 totals: L-Dopa as Sinemet--500 mg Amantadine --200 mg Mirapex--2.25 mg ENADA (reduced NADH) 2.5 mg I started slow and worked up to this dose over several months, I also reduced Sinemet simultaneously (from 700 mg a day) Regards, WHH 54/18