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Hi Brian, you wrote............ > Please could you tell me how your medication are performing. > How many tablets you are taking. > Are you getting any side affects. > Have you reduced you intake of Ledopa. > Or any thing else you may have to say. > By the way Tasmar costs $366 Australian.It may be on Gov med list in Oct this year for $3.20. > Yours inantisapation Brian England. > Brian, I take a 200mg. Tasmar tablet and a 50/200 Sinemet CR at 6:00AM, at 12:00 Noon, and at 6:00PM. For myself Tasmar produces a very smooth ride with few perceptible on's and off's. I only feel off when I first get up in the morning or when I forget to take my meds and run over a few hours. The only side effects I experience are: occasional nausea 1 to 2 hours after my 6:00AM initial meds (probably the Sinemet) darkened urine (the Tasmar) loose stools (the Tasmar) a plus! Brian, initially I did reduce the Sinemet but now (15 mo. later) I am pretty much back where I was and it seems to be correct. I still work full time. We just vacationed in California and I got the experience of real freeway traffic stress and the meds did not let me down. Tasmar is about $350.00 / 100 tablets here as well and will soon be added to the formulary lists as an approved-for-reimbursement medication in B.C. Canada. Best regards..............Murray [log in to unmask]