The following article was directed towards throat cancer patients who'd lost their sense of taste due to radiation therapy. However, since Parkinson's patients also lose much, if not all, of their sense of taste due to PD, rather than any treatment or therapy, I couldn't help but wonder if the taste restoring benefits mentioned in the article might not benefit the PD community. Has anyone here on the List used zinc sulfate for ANY reason and found their sense of taste happened to benefit? Barb Mallut [log in to unmask] --------------------------------------------- NEW YORK (Reuters) -- People who have radiation treatment for head and neck cancer often lose their sense of taste, but zinc sulfate tablets can help reduce this side effect, and also resolve the problem more rapidly, report Italian investigators in the May 15th issue of Cancer. Results from previous clinical trials suggested that zinc sulfate tablets ``-both prevent and correct taste abnormalities-'' in head and neck cancer patients undergoing radiation therapy. In an attempt to confirm this in a controlled setting, the group randomly assigned 18 head and neck cancer patients to take a placebo (''dummy'' pills) or 45 milligrams of oral zinc sulfate three times a day at the onset of any taste abnormalities related to radiotherapy. The patients took the tablets for up to 30 days following treatment. Dr. Carla Ripamonti and colleagues from the National Cancer Institute of Milan, Italy, report that zinc sulfate was well tolerated and ``-slowed down the worsening and accelerated the improvement of taste acuity in a clinically and statistically relevant way.'' Zinc-treated patients also tended to recover their ``taste sensitivity'' more quickly than patients who received a placebo. The team believes, based on these findings, that oral zinc sulfate administration could become `routine'' in the care of head and neck cancer patients undergoing radiotherapy. SOURCE: Cancer (1998;82:1938-1945)