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Hi Donna ! I’ve experienced muscle cramps , off and on, all my life. But since I was diagnosed as a PWP almost five years ago, muscle cramps have occured more frequently . Somehow, I discovered a banana at the onset of a cramp will relax the muscle within minutes. But your friend Joe may not wish to be seen munching on a banana at his desk. Then he can have a banana with cereal every morning because that seems to do the trick .It could be the potassium in bananas but I am not a doctor. I suggest Joe discuss the problem with his neuro. Good luck, Karl