Hi Since my most serious symptom is end of dose dyskinesia , I have been trying various ways to relieve it . Taurine . This is meant to be a neurotransmitter that calms the nervous system down . Taking 1000 mg caps at the time of dyskinesia produced no obvious improvement GABA This is meant to be another neurotransmitter that calms the nervous system down . Taking GABA plus caps (100 mg of GABA ) at the dyskinesia time produced little/no obvious improvement . GHB This is a substance that occurs naturally in the brain and its function seems to be poorly understood .Taking about 1 gram of GHB about dyskinesia time seemed to suppress the dyskinesia effectively . I am awaiting the arrival of my second order , to make more extensive trials . I also wish to try the potassium version to see how it affects PD symptoms . I will post results when trials are done . GHB has been banned in many places and unlike many substances available on the Web it really has an effect . Anyone using it should do it with caution . peace Alastair ( [log in to unmask] )