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John - you asked:
>>> Jbtwelv <[log in to unmask]> 05/21/98 12:39pm >>>
>>>If you can recall the reference to difficulty with estimating
time (how long something will take to get done), or if anyone
can offer further evidence or documentation of this
phenomenon<<<
John Bachman

John:
     The human brain has an internal system for measuring
the passage of time.  The system involves the substantia
nigra and the brain striatum.  Both of these areas are
implicated in PD.  The neurotransmission of dopamine acts
to push the watch forward.  Lesions of the substantia nigra
and/or the striatum slow or stop the timekeeping system.
Levodopa has been shown to restore an accurate sense of
time.
     For more info read: Science magazine, 1996, issues 271
and 272.
   Stephan 53/7