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In a message dated 5/30/98 11:15:30 AM Central Daylight Time, [log in to unmask] writes: << if it only works for one year which is what all reports about the drug say, then will it work again at some later stage of the disease"? Or are they saying that it will continue to be of some benefit for many years, from early stages to late stages. I am taking it now as my only PD med, is it some help, but not a lot. I have tremor as only symptom. Anyone have any clue? >> Maybe this is what you want to know: My Amantadine has continued t o exert its anti-Parkinson effect for about 15 years now. While it is weaker than other drugs, I miss it as soon as I stop it. However, the powers that be in the physician community have only recently discovered its anti-dyskinesia effects as significant. Regards, WHH 54/18