Sat, 30 May 1998 15:08:57 -0400 Ron Reiner <[log in to unmask]> wrote on the subject: "Zoloft and Eldepryl Contraindicated": <SNIP> >SIDE EFFECTS OF SSRI ANTIDEPRESSANTS >+ Nausea, diarrhea, headache, sleepiness, loss of appetite, fatigue and >problems having an ejaculation >+ Prozac and to a lesser degree Zoloft, can cause tremor, insomnia and >anxiety. >+ If taken in the morning, Paxil and Zoloft can cause excessive sleepiness. >+ Note: On occasion these medications can actually worsen the symptoms of >Parkinson's disease or cause a sense of physical restlessness. >CONTRAINDICATIONS >When combined with Eldepryl (selegiline), these medications can uncommonly >cause a severe syndrome characterized by increased rigidity, jerking >movements of the arms and legs, agitation, confusion, restlessness, fever, >shivering and sweating ("serotonin syndrome"). The simultaneous use of >these medications and Eldepryl should be discussed with your physician. <SNIP> Hello Ron and all, On this list I read about the possible positive effect of seretonine on PD. So when I visited my neuro I suggested it and he prescribed at first Prozac. Since I was not happy with this because of the presumed addicting effect of Prozac, he prescribed Serotax (paroxetine) (= Paxil in USA). I knew someone else who used it, so I read the paper included with his meds. I have to mention I use Eldepryl (2x5,0mg/day). The paper said, it couldn't be used with a MAO-inhibitor (as is Eldepryl). I decided to test the system and went to the pharmacist and gave the prescription. After a while he came back and told me that the computer with all my meds in it indicated that I couldn't take this drug-combination. He phoned the neuro, who admitted his mistake and prescribed another med. Luckely the computeralarm worked good THIS time. Thanks to warnings on this list I was alerted. This "adventure" has made me decide to stay extra alert and check first everything they prescribe me. Starting with this new med I got (but haven't used yet!). Greetings, Hans.