In checking my somewhat darkened memory banks, (15 years worth of trying every PD drug that hits the great common market can have a dimming effect) , i.e.,I was one of the first to try Eldepryl, which i think was 1981 or 1982 (aka Deprynel, aka Selegiline). Here's an approximate list--Immediate release Sinemet 25\100 (aka El Dopo's replacement), Sustained release Sinemet 50\200( aka Sinemet CR), Artane(aka trihexyphenidfyl),Parlodel (aka Bromocriptine), Permax(aka Periglide, Xanax (aka alfraprolazem (sp?), Requip (aka Robiniperole), Mirapex{aka Tolcapone) and Amantidine (aka Symmetrel). I know I forgot something but anyhow, that last stuff ain't new. I took for 6 or 7 years til last Nov. I had (have} very litle dyskeneitic (Your spelling of that word grades higher that than your spelling of the Symmetrel generic-AMANTADINE Hydrochloride) problems and have no idea why Neuro prescribed it. I haven't missed it yet, I don't think. My diatribe is almost done--a short word re Parkinson meds---My local Neuro called me (yes- He called me, proud as a peacock, to prescribe the NEW Tasmar, which he said was just approved but not out yet. When I told him that I had been to the Mayo in Rochester and had been taking Tasmar for more than a month and asked him why ha was so far behind-- He said " I guess the salesmen were late getting here" I will not dwell on that---It says a whole whatever your question was----the answer is--Whatever is today will not be tomorrow so liveach day to it's fullest.