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In a message dated 98-06-05 09:35:57 EDT, you write: << I have read a bit about a procedure called a pallidotomy, where a globus pallidus pathway is disrupted to reduce Ach inputs. Does anyone know anyone who has had this? Whats the general opinion about this treatment?. >> You have definitely come to the right place. There is a whole wevbsite devoted to palli/ transplant surgery. Find it at: http://www.parkinsonalliance.net/hihgang/pall/ Good luck to you and your friend. Regards, WHH 54/18