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Ian Galbraith wrote: > > My mother has had Parkinson's disease now for about 15 yrs > and during the last 3 - 4 yrs she has developed an > incresingly debilitating blepharospasm, worse in the right > eye. Botulinum toxin injections were tried, also to the > pretarsal area, without improvement. She > had an MRI scan which showed a few old infarcts in the brain > but these did not seem to explain the spasm. > I was wondering if either doxorubicin injections or surgery > would be of any potential benefit to her. Would the surgery > involve GA? Ian, your questions sound as if better addressed to a very competent specialist in ophthalmology, Parkinson's disease, or both- I hope you have access to such advisers. I don't understand the reference to doxorubicin, an extremely toxic anticancer drug that kills virtually anything in its path. Requires utmost care even when it is given IV (in hopes of reaching the cancer site via blood circulation), as the slightest leakage from the vein puncture will kill surrounding tissue. Is that a viable option? J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013