This is the second time in two weeks this has happened. She probably get dyskinesia. You might counteract it by eating protein. The lady last week took 700 mg. or more. Call your doctor if possible. Watch her carefully. jjjane >Becky, not paying attention, just took twice her usual dosage of 50/200 CR >Sinemet. Does anyone have any idea of the affect on one who does this? > >Thank you. >Jeff part time CG for Becky, 52/16