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Murphy's law: this will only happen on weekends. jjjane >Jeff, >You wrote: >> Becky, not paying attention, just took twice her usual dosage of 50/200 CR >> Sinemet. Does anyone have any idea of the affect on one who does this? >> >> Thank you. >> Jeff part time CG for Becky, 52/16 >> > >Jeff, on June 6th. '98 Margaret Tuchman took her entire day's Sinemet >at one go and here is her posting the following day........... > >Margaret wrote: >God, what a HIGH!!! I don't know if it is the 750m mg of regular >Sinemet or knowing that YOU CARING & WONDERFUL people are out there. >WOW!! > >I am ok- spoke to the doctor, pharmacist and checked internet. One >does not need to worry below 1500 mg. I am woozy, dizzy and a bit >nauseous. > >My husband, Marty, prepared a plate full of PROTEiN and for the 1st >time in years, I ate protein during the day. > >The reason I took 7.5 pills (10/100s) all at once is because I'm >taking liquid sinemet trying to titrate my dose carefully - looking >for that magical balanced line between decreasing sinemet and >increasing Tasmar. > >Love you ALL!!! > >Margaret > >Now Jeff, that said, you should still read this next post from >Margaret & Gail Vass on the same subject: > >Dear List Friends, > >Again, I want to thank everyone who responded to my urgent call for >help on Saturday when I mistakenly took 750 mg of regular Sinemet. I >do have a reasonable (somewhat) explanation of how "it" happened, >though I did enjoy reading some of the less serious comments >questioning my basic math skills. > >I dissolve my daily dose of Sinemet into 1000 ml orange juice or Tang >and take 100 ml of the mixture every 2 hours. Since Marty was home, >he took over the job of mixing and apportioning the mixture into 10 >bottles. I did not know > >that he had not finished the process and when I went to take my >drink, I mistakenly gulped down the undiluted mixture. When he >realized what I had done, he screamed a lot but also fixed me peanut >butter sandwiches and milk. I called my doctor - away on vacation, >and spoke with a neuro-resident on duty. After explaining to him the >theory behind liquid Sinemet, he thought I should have my stomach >pumped. He asked if I have a history of cardiac, blood pressure, or >liver problems. I don't! He also said that I will probably >experience dyskinesias and nausea. Since he could not proscribe >medication, he suggested I call my GP and get Compazine for nausea. > >The pharmacist told me that taking1500 mg of Sinemet would be cause >for real concern. > >Observations and Questions: >1/ It is nice to be able to eat protein during the day and it is >wonderful not to have to take medication every two hours. >2/ I had NO dyskinesias, until 7 hours after taking the meds, when I >had minor end-of-dose dk. just before I started to tremor and I knew >I needed more Sinemet. How come? >3/ I felt good, I had energy - I was high! I was able to work, >shop, garden. >4/ I am told that I was "not my usual self" (?) - my speech was >slurred, I was slow in my thinking. This is opposite to what I >felt. I suppose that the feeling of euphoria is quite common when >taking cocaine, or other stimulants? >5/ if the half life of regular Sinemet is approx. 2 hours, how come >I had a 7 hour free ride? Is the therapeutic effect cumulative? >6/ since 750 mg lasted 7 hours, does that mean that I really need >100 mg per hour and basically I am always under medicated? Hello, >Brian??? >7/ what role does Tasmar play in this equation? I've been >taking 300mg per day and had cut my Sinemet from 1100 to 750. But, >the last week I was not holding the "ON" for the two hours. I was >given the advice that perhaps cutting the Tasmar in half would extend >the ON. I really had no chance to give this alternative a proper >trial yet. Another complication has arisen, I am having the "Tasmar >Runs" and from what I understand, once that side effect happens, >there are only two alternatives, cut back on the Tasmar or stop >taking it. >8/ While I felt really fine the day of the OD, I was a rag the day >after and even most of the day today. I am tired and slow moving, >though I get plenty of rest in the bathroom/WC/loo. > >So, dear comrades - take my experience and see what we can learn. > >A health professional, List member, caring friend wrote the >following: > >Date: Sat, 06 Jun 1998 20:13:25 -0400 >From: Gail Vass <[log in to unmask]> >To: Margaret <[log in to unmask]> > >Margaret, > >I'm on the Digest form of the PD list so I just received your URGENT >message...I did get to see your call for help, others responses and >your note getting back to the group saying what action you had taken. > >I must admit as a nurse I had some concerns about you posting such a >note althought I certainly understand why you utilized this resource. >I hope you don't take this as criticism of you or of what you did in >posting it to the list but I thought that this would be an opportunity >to discuss emergencies and this list. > >Something along the line of: > >Subject: > When you have a potential overdose > >Always call your Doctor.. >Always call your Pharmacist >Always call the Poison Control Center >Call 911 when you think you may have an emergency. >Always remember your local Emergency Room. > >When you have a potential overdose, chest pain, or a bad fall seek >emergency medical treatment. This list should never be relied on for >emergencies. You may not be conscious to read the replies and waiting >for replies could cause a serious delay in treatment.. And even the >most well intentioned replies may not be medically sound advise. Some >delays in treatment can have serious consequences. > >Some poisons SHOULD NOT be vomited back up. Some sudden sharp pain may >be the only warning you get. Some replies may be incorrect. > >I'm just looking at this as an opportunity to remind and caution >people...what are your thoughts? > >A big hug, > >Gail > > > >[log in to unmask] >DOB: 1941/Dx: 1980/Cured:ASAP >Slogans wont do it/Hard work will > > >So Jeff, do not panic. Take Gail's advice please and once again, do >the following.......... > When you have a potential overdose > >Always call your Doctor.. >Always call your Pharmacist >Always call the Poison Control Center >Call 911 when you think you may have an emergency. >Always remember your local Emergency Room. > >I wish you and Becky all the best.........Murray 53/4 >[log in to unmask]