Dear Julie Ann: I believe what you are experiencing is the result of the lack of dopamine in your body. I too felt fatigued for years before my diagnosis at age 34. I still feel that way now (10 years later) when the durgs wear off. At these times I also lose my ability to be articulate, and to mentally juggle more than one thing at a time. As far as progressing to both sides is concerned, it behaves differently in different people. If you are not on medicaion right now the doctor could have done you a disservice by not putting you on at least one of the drugs that is suppposed to have a neuroprotective effect. As I'm sure you've seen on this Website, however, the jury is still out on that topic. Some people believe they do more hamr than good. Don't know what else to say, except that the better inforned you are about your illness, the better you'll be able to help your doctor help you. They have a pretty good idea what you're going through, but then again, they're not there at 3 a.m. They're not there when you have to wake your husband to pull the covers off you and help you out of bed to go to the bathroom because you're afraid you'll wet the bed if you expend the effort to do it yourself. They're not there when you have to crawl on your hands and knees to the bathrrom so you won't fall. And they're not there when you just want to scream because you can't mve and you feel like you're trapped inside your body. there wh