Alistair-- my own "working definition" of dopamine agonist is that it is a med which works WITH or imitaite the action of dopamine, as opposed to an ANTAGONIST which works AGAINST the dopamine . For example, opiates are "dopamine antagonists" which as I understand it compete with the dopamine for the receptors in the brain. Correction anyone??? SNIPPED >My dictionary defines " agonist " as " one engaged in the struggle " >. Can "dopamine agonist " be used of a substance that boosts the >dopamine effect ( Like suppressing the MAO B that destroys the >dopamine ) ? Can it be used of a substance >that substitutes for/mimics dopamine ? >I am far from certain that I am the only person for whom " dopamine >agonist " is too vague to have any real meaning ,except that it >appears to help the dopamine neural transmission pathways of the >brain , in some vague and undefined way . This seems to include >all/most PD medication . Camilla Flintermann, CG for Peter 80/9 Oxford, OH [log in to unmask] "http://www.newcountry.nu/pd/members/camilla/one.htm" My Home Page * * * * * * * * * * * * * * * * * * Ask me about the CARE list for* * Parkinson's caregivers ! * * * * * * * * * * * * * * * * * *