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In a message dated 6/20/98 4:54:49 PM Central Daylight Time, [log in to unmask] writes: << A drug that has affinity for and stimulates physiologic activity at cell receptors normally stimulated by naturally occurring substances, thus triggering a biochemical response. >> On these points the package insert was either unnecessarily confusing or patiently wrong: The term "agonist" does mean a substance that mimics the action of the other (drug -as in "dopamine agonist"). Dyskinesias are indeed involuntary movements. They are brought on by years of exposure teamed with acute exposure to l-dopa. A Dystonia although rarely thought of as a movement, can move limbs and even torsos. In commonly used terms, these are much like a cramp. They too are brought on by years of exposure teamed with acute exposure to l-dopa. I hope this helps and doesn't involve too much "guilding the Lilly." Regards, WHH 54/18