> From: Hans van der Genugten <[log in to unmask]> > Subject: Re Alastair Wyse: Dopamine-agonist definition? Hi Hans > > > 1. <anatomy> A prime mover. > Aristotelean philosophy ?>>>> > Sorry this was my feeble attempt at a joke . In Aristotelean philosophy everything is reduced to change and move ment . Thomas Aquinas took this philosophy and defined God as " The prime mover " that is the cause of all change and movement .( It is over 30 years since I studied any philosophy so I am depending on my not very good memory ) The joke was to illustrate that different meanings can be attatched to the same words . > <<<< If the term " dopamine agonist " is confined to a replacement > neurotransmitter for dopamine then it has meaning.>>>> > > YES! I am glad you are so confident . I unfortunately have had in the past great difficulty understanding what people are saying using this strict definition . > > <<<< > But I would like to give an analogy of why I made the original posting. > The original posting concerned the term " dyskinesia ". I feel > knowledge is like an ice skater skating on the ice of language . As > more and more people use the word "dyskinesia " in the same way the > ice gets thicker and one can skate more confidently over it. But in > Judith's posting some medical people were redefining the term " > dyskinesia ".>>>> > > I think that the word "dyskinesia" was NOT redefined, but was defined in a > complicated and detailed way. So the definition was correct! Here I think your confidence is definitely misplaced . Here is the relevant part of the original The most common side effects of Mirapex taken > with levodopa observed in clinical trials for advanced-stage > Parkinson's disease were postural hypotension (low blood pressure > caused by a change in posture), dyskinesias (impaired movement), > extrapyramidal syndrome (involuntary movements), insomnia, dizziness > and hallucinations . This article redefines " dyskinesias " as impaired movements the word I and a lot of other people use for slow movement is bradyskinesia . On this list usually, and always by me, dyskinesia is used to describe involuntary movements ( usually a side effect of dopamine boosting drugs and this usually means l-dopa ) . This latter is redefined in the article as extrapyramidal syndrome . peace Alastair ( [log in to unmask] )