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> From:          Hans van der Genugten <[log in to unmask]>
> Subject:       Re Alastair Wyse: Dopamine-agonist definition?

 Hi Hans

>
> > 1. <anatomy> A prime mover.
> Aristotelean philosophy ?>>>>
>
Sorry this was my feeble attempt at a joke .
In Aristotelean philosophy everything is reduced to change and move
ment . Thomas Aquinas took this philosophy and defined God as " The
prime mover "  that is the cause of all change and movement .( It is
over 30 years since I studied any philosophy so I am depending on my
not very good memory ) The
joke was to illustrate that different meanings can be attatched to
the same words .

> <<<< If the term " dopamine agonist " is confined to a replacement
> neurotransmitter for dopamine then it has meaning.>>>>
>
> YES!
I am glad you are so confident . I unfortunately have had in the past
great difficulty understanding what people are saying using this
strict definition .
>
> <<<<
> But I would like to give an analogy of why I made the original posting.
> The original posting concerned the term " dyskinesia ". I feel
> knowledge is like an ice skater skating on the ice of language . As
> more and more people use the word "dyskinesia " in the same way the
> ice gets thicker and one can skate more confidently over it. But in
> Judith's posting some medical people were redefining the term "
> dyskinesia ".>>>>
>
> I think that the word "dyskinesia" was NOT redefined, but was defined in a
> complicated and detailed way. So the definition was correct!

Here I think your confidence is definitely misplaced . Here is the
relevant part of the original

  The most common side effects of Mirapex taken
> with levodopa observed in clinical trials for advanced-stage
> Parkinson's disease were postural hypotension (low blood pressure
> caused by a change in posture), dyskinesias (impaired movement),
> extrapyramidal syndrome (involuntary movements), insomnia, dizziness
> and  hallucinations .

This article redefines " dyskinesias "  as impaired movements the
word I and a lot of other people use for slow movement is
bradyskinesia .  On this list usually, and always by me, dyskinesia is
used to describe involuntary movements ( usually a side effect of
dopamine boosting drugs and this usually means l-dopa ) . This latter
is redefined in the article as extrapyramidal syndrome .
     peace
          Alastair     ( [log in to unmask] )