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p. l. maddux wrote: > > Hi Friends, > My sister brought me a printout from a website called "Friends of > Israel". (foigm.org). Under the headling "New drug for Parkinsons > paients, it says, The new drug called L-Dopa ethyl ester was developed > by Prof Daphna Atlas of the Hebrew University and Prof Eldad Melamed of > the Rabin Medical Center-Beilinson Campus, and financed by Teva > Pharmaceuticals. The material, synthesized in Atlas's lab in Jerusalem, > has three US patents. > This was dated Feb/March 1998. Has anyone heard of this? Yes, it's a formulation that can be injected instead of taken by mouth, thereby avoiding the nausea that afflicts some patients: Djalderti R, Melamed E; Ann Neur 1996;39:400-404: A hindrance to levodopa absorption is its poor solubility. A new precursor, levodopa ethylester (LDEE) injected subcutaneous or intra-muscularly is well tolerated, reduces off-on fluctuations, and avoids side effects of oral administration. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013