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At 10:31 PM 6/30/98 EDT, you wrote: >Dad is taking Sinemet CR 25/100 and would like to know if he can take it with >a meal. He knows he's not supposed to take Sinemet with a meal, but he would >like to know about Sinemet CR since it is time released. Trish > Trish: Sinemet CR can be taken at meals. My neurologist has me doing so. However, there may be some slight loss of efficiency. Incidentally, did you know that a CR tablet is only 60% as effective as a regular Sinemet of the same strength? My old neurologist didn't, so I changed to Mayo Clinic. Good luck. Bill Butch <[log in to unmask]>