My doctor told me to take sinemet and permax on an empty stomach for maximum benefit. Hope that helps. -----Original Message----- From: Trish Scarmuzzi <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Date: Tuesday, June 30, 1998 9:41 PM Subject: Sinemet CR >Dad is taking Sinemet CR 25/100 and would like to know if he can take it with >a meal. He knows he's not supposed to take Sinemet with a meal, but he would >like to know about Sinemet CR since it is time released. Trish