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One more for the CD follow up. Yes I suffer and have been at the bottom of the pit. I started at the bottom dose of Paxil and rose to more than any of the doctors wanted to give me. It just was not doing me any good. I tried Zoloft and it did nothing. About 6 weeks ago I was put on Prozac. It has helped, but not completely. Now, a little over a year ago I had surgery for an ulner neuropathy in my left arm. It was very painful--nerve pain, on fire. I was given Imipramine(an anti-depressant which has a side effect of stopping nerve pain). That surgery was very successful. My left arm is doing great, better even than the surgeon thought it would. However, a month ago my right arm started hurting. The neuro said it is the same thing, this time it is aggravated by my pd tremor and muscle rigidify. I have once more been given Imipramine for the pain while I go through the testing. The amazing thing is that for the first time in close to 10 years, I am not depressed. Just look at the length of this note. And being on the radio, writing for the newspaper, and feeling like doing something. I believe that the combination of the two drugs has done the job. WOW don't forget how to laugh (and do it often) Marling McReynolds [log in to unmask] http://members.tripod.com/~marling