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Mom started taking Sinemet CR once daily and now taking 1 in the morning and 1 at night. I noticed that since she added the second sinemet, that she seems to be "impatient" and in a rush to get things done (well, in a rush in her world). The 10/100 generic sinemet 4 times daily had the same effect. Is this a typical reaction to sinemet? Thanks! Kathy Barras (cg mom, Florence, 74/Sept 97) [log in to unmask] Fort Lauderdale, Florida