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This could be the result of distention of small veins / capillaries. Isosorbide dinitrate expands blood vessels. Cardizem is a calcium channel blocker which can cause "edema." Mevacor is a cholesterol blocker which can make the vein walls less thick. Aspirin can also cause the problem, purpera. Will Johnston ---------- From: jim and emily jackson <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Subject: Re: blotchy discoloration Date: Monday, July 06, 1998 10:05 PM >> Still do have the red and blotchy discoloration on both legs from about >> 6inches above ankles and down. Any comments on how to rid these? > I have blotchy discolorations all over my arms. Don't know why, would like to know. I take Mirapex, eldepryl, cardiziem, isosorbide (nitro), mevacor, and various inhalers. Also, regarding recent comment from someone about scalp flaking, I have personally found some relief by using Selsun Blue shampoo. Jim Jackson [log in to unmask]