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Jim: Thanks for responding with the detailed med history. The weight gain (from Mirapex?) is intriguing, as I have experienced the same problem -- having gone from 175lbs to 189 lbs in the span of about eight months, It's also interesting to note that as a relatively new pd inductee, that you also have encountered the bloating and swelling. I haven't forgotten my promise of summarizing the observations from the list participants. Thanks again. John Faus [log in to unmask]