Dear Pete: I need to share my experience with you concerning Cogentin. I take Sinemet and Permax. Before I took Cogentin. I was a mess. I did not know where anyone was. Could not tell if it was daytime or nighttime, kept asking my husband. (I'm sure I drove him crazy) I just kept getting worse. I was sleeping all the time. I had no memory,I didn't even know who I was. Forgot to pay bills, make deposits, etc. Gina 47/7 mos