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My mother (73/3) has recently been diagnosed with osteoporosis. Her score on the CT bone density study was 4 standard deviations below the mean of 35 year old bones. Osteoporosis is defined as 2.5 standard deviations below the 35 year old score. Her doctor has recommended that she take Fosamax (10 mg a day). She is already taking sinemet 25/100-4 times a day premarin (estrogen replacement) .625-once a day medroxyprog Ace (goes with estrogen replacement)-5 mg a day She wants to know if anyone on the list has had experience taking sinemet with fosamax and what problems (if any) they had. She'd also like any information about managing PD and osteoporosis together. Thanks Jane (daughter with 42 year old bones) Jessie (73/3) [log in to unmask] We both read the list!!