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Hi Ken, I've been sorta "off" these days and missed some of this I suspect. You wrote.... SNIP When people have to cut pills in half , when it is NOT reccommended, to be able to afford the pills, that is just the tip of the iceberg! I imagine the funeral industry must love HMO's.............. [log in to unmask] Ken, the neuros here seem to often prescribe the Sinemet CR 200/50 CR here in BC. whether they are prescribing whole or half doses. The monograph available on the Internet at: http://www.rxmed.com/monographs/sinemet2.html discusses the bioavailability of 2 half tablets compared to an intact tablet and later under dosage states "Sinemet CR 200/50 may be administered as whole or as half tablets. Sinemet CR 100/25 should only be administered as whole tablets. To maintain the controlled release properties of the product, tablets should not be chewed or crushed." (If I feel the need for a quick boost, I chew half a Sinemet CR 200/50 and feel the effects in 15 minutes) That said I'm reasonably sure it is prolly better to take standard Sinemet if you want the quick med. I just don't always carry it with me but I do always have CR. I don't know the exact price of the 2 sizes of CR but I think it may be cost effective to purchase 100 Sinemet CR 200/50. (as opposed to two purchases of 100 Sinemet CR 100/25) The bottom line here is I think it is ok to split the scored Sinemet CR 200/50 and I don't follow where doing so is a benefit to funeral homes. All the best Ken and its ok ta be feisty even if ya may be just a litttle misguided on this one........ murray [log in to unmask]