Good afternoon, The 50/200 CR sinemet that is scored was meant to be scored. My dr. told me to break them when I needed to reaction time to be more quickly than the normal 45min. to 1hr. amount of time the CR reaction time. The reason for the CR is to give have a medication that lasts from 2and 1/2 hrs. -3 hours. Yes, if you break the CR you will get a little speed up in the reaction time and possibly a very small of loss in the 3hr. life of the CR. Hope you have a good day-----pete