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---------- > From: Mary Jean Gunden <[log in to unmask]> > > What my Mom forget to mention to the neuro at his appointment is that he has > fairly recently (4 months) begun receiving injections of Lupron depot for > treatment of prostate cancer. It may be coincidental that the cognitive > decline occurred since he began the treatments. Does anyone have any > experience with this? My husband, Steve(79/1) has been on Lupron for almost 8 years. When I first got concerned about his decline, I tried to get the urologist to take him off Lupron completely. The best he would agree to was to skip one of his quarterly shots last year. > I did some searches, and there is some anecdotal information that there could be a connection. I also >found one reference that described the substance as a dopamine antagonist (NOT agonist), and I > assume if that is the case, it could cause big problems for someone who > already has a problem with dopamine. I, also, would like to hear from anyone with information on the interaction of Lupron and Parkinson's Disease. My husband is on no meds for PD as the side effects of the Sinemet were worse than the symptoms of the disease. Ellen Peck