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Over the curse of my wife's PD - ~20 yrs - we have been seem about 12 neurologists( didn't realize so many until I just counted up ) and at various times as they changed dosages they all went through changes that involved half pills. When the CR tablets became available I questioned the breaking but the NR said it was OK - that was #5 or 6 - I cant remember which NOTE - the large number of NRs is due to our moving and also the NRs moving - plus dissatisfaction with a couple of incompetents. ( I just noticed I misspelled course -- my subconscious must have taken over ???) Bob Anibal CG for one helluva gal 78/~20