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hi all, Does anyone know about this sort of thing...got me kinda worried.. I don't mean to alarm anyone...of course...but my friend that was taking 2 Sinemet 10/100 every four hours just recently went into the hospital for a knee replacement and while she was in the hospital she had a heart attack...the dr said she was taking too much sinemet, she also had given a pint of blood before the surgery which was last tuesday...and after giving the blood she was really dizzy and kept being dizzy for some time... I am concerned because my hubby is on Sinemet 50/200 twice a day and then reg sinemet 25/100 at nite...he seems fine but I will ask the dr just the same. gosh...we don't need any heart attacks do we!.......... i don't know all the details....my friend has restless legs not pd.....her legs are better now and all she is taking is quinine...not sinemet... Coleen :-) Oregon...Missing Links adoptees support group ~~a proud member of the Heart of Triad mail list**~~ [log in to unmask] 541-862-2226 http://www.barysoftware.com http://members.wbs.net/homepages/f/r/e/fredmom.html http://geocities.com/Heartland/Ridge/9923/adoption.html Http://members.tripod.com/~StateMailingLists/index.html