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Judith - I am confused as to the timing of the marketing of this patch. Any
idea when it will be available?

                                Bob Dolezal

At 3:36 PM 8/3/98, Judith Richards wrote:
>Monday August 3, 1998
>
>Company Press Release
>
>Schwarz Pharma and Discovery Therapeutics Announce Plans for
>New Transdermal Patch for Parkinson's Treatment
>
>MEQUON, Wisc. and RICHMOND, Va.--(BUSINESS WIRE)--Aug. 3, 1998--Schwarz
>Pharma, an international pharmaceutical company with US headquarters in
>Mequon, and Discovery Therapeutics Inc. (DTI), a privately held company
>in Richmond, today announced an alliance to develop DTI's novel dopamine
>agonist delivered in a transdermal patch for the treatment of
>Parkinson's disease. Schwarz Pharma will be responsible for
>completing development of the transdermal patch and for worldwide
>marketing, except in Japan.
>
>``The patch revealed strong safety and efficacy features in a clinical
>phase II study,'' said Patrick Schwarz-Schutte, president and CEO of
>Schwarz Pharma AG. ``There has been a long-standing need for a
>once-a-day medication for Parkinson's disease, and thus, this is an
>excellent fit with our strategy of global search and development for
>treatments that can address unmet medical needs. We welcome this
>cooperative agreement with DTI to develop this innovative product.''
>
>Parkinson's disease is a chronic, <snip>
>
>Discovery Therapeutics Inc. developed this novel dopamine agonist
>(N-0923) in a transdermal system to deliver the drug in a once-a-day
>patch. According to Dr. Donald A. McAfee, president and CEO of Discovery
>Therapeutics Inc., ``This is a significant step in the treatment of
>Parkinson's disease, and we expect that this patch will provide patients
>with more consistent control of symptoms and fewer side effects.'' Dr.
>McAfee also noted that most Parkinson's patients must take several
>medications each day to control symptoms, and the convenience of a
>once-a-day patch would be a welcomed improvement.
>
>Copyright =A9 1998 Business Wire.
>--
>Judith Richards, London, Ontario, Canada
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