Like Ida, upon awakening, I can usually go for about two hours without any drugs - IF I don't start doing things 'round the house. Remaining calm and relaxed is MY personal key to not initially needing them stinkin' drugs the minute I get up. I've noticed, again, like Ida, that IF I should happen to take my first meds of the day relatively soon after awakening, I don't get the full med-benefit that I get with the delayed start-time. In fact, my entire drug schedule for that day is thrown off, and I have to kinda feel my way along throughout the day when it comes to taking any subsequent drug doses. I'm pretty savvy about my own PD, so that's not impossible, but it's much easier to be on my usual regular time schedule. By the way.... I did NOT have that 2 hour "grace-time" upon arising prior to my Oct., 1994 pallidotomy. It was just one of the beneficial results of that blessed surgery.... Barb Mallut [log in to unmask] ---------- From: Parkinson's Information Exchange on behalf of Ida & Andre Kamphuis Sent: Wednesday, August 05, 1998 12:37 PM To: Multiple recipients of list PARKI Re: mornings At 13:28 5-8-98 -0500, you wrote: >When I wake up in the morning I can go for an hour or more not needing any >medication. Tremors are my main problem but it seems strange to me that >after all night you wouldn't be in great need of something. Is anyone >experiencing this? > >Marianne Rome 6l /l51/2 Yes I am experiencing this. In fact I can go on for two hours, if I don't try to do things with much effort. I once read something about it and it was called sleep-benfit. Starting the first sinemet not before two hours after I've gotten up, I benefit more from it than if I start it immediately after I've gotten up. The only symptom which sometimes shows up during this drug-free period is a tremor, which is totally absent the rest of my day. The symptoms, which are the most troublesome are a combination of dystonia and dyskinesia which starts in the evening 3 or 4 hours after I took my last sinemet and lasts about 1 hour. Ida Kamphuis sinemetCR 100/25 1 and 1/2 each day 54/14 sinemet gen. 100/25 1/2 each day Tasmar 100 2 each day eldepryl 2 each day permax 0.05 7 and 1/2 each day orphenadrine 50 5 each day -------------------------------------------------------------- Vriendelijke Groeten / Kind regards, Ida Kamphuis mailto: [log in to unmask]