On Thu 06 Aug, Ida & Andre Kamphuis wrote: > (snip) > The literature about sleep benefit says it is common and reported by 30% > to 40% of the patients. It has no relation to quality of sleep and it > is more frequently reported by young -onset patients. > > Thinking over things like this , I hope to see some clustering of > symptoms that would divide us PWP's into type A and B or X and Y. Does > any of the research-wise members know whether a factor analysis is ever > tried on patients and symptoms? > > > </bigger></bigger></fontfamily><bigger>Regards, Ida</bigger> > > > > -------------------------------------------------------------- > > Vriendelijke Groeten / Kind regards, > > > Ida Kamphuis mailto: [log in to unmask] > > I have made some observations which relate to sleep, and which may be of interest. I have found that taking my normal daily dose of Madopar before going to bed, left me feeling mentally over-stimulated; I lay wide-awake with my brain buzzing away - not at all a good way to go. If I took no Madopar, I tended to have a very restless night, waking up evey 2 hours or so. I found that if I took about half the normal dose of Madopar before going to bed, It is just about ideal, and I have continued to do this for the last 5 years or so. I take a Madopar CR (100 mg levodopa). Effective life is 4 hours, just like Sinemet CR, but the levodopa is halved. Another effect I have noticed is that I get what I like to call a 'Free Ride" in the morning; its duration and effectiveness seem to relate to the number of hours sleep I get. My neurologist thinks it is merely the last remnants of the previous day's tablets, but to me there is a subtle difference which I cannot explain, but which says 'this is real'. Maybe there is a small ammount of re-generation during those hours of sleep? Not much use if it only lasts half an hour, but worth keeping in mind. One final point; I believe that like many subjects relating to effects of Parkinsons on ourselves or other PWPs, it is important to define our Age and years since diagnosis. My comments above refer to my experience over the disease duration 10 to 19 years: It would be pointless (I believe) to compare the observations with those who have (say) 4 or 5 years of Parkinson's Regards, -- Brian Collins (58/19) <[log in to unmask]>