I KNOW that a severe reaction that I had to the drug compazine years ago definitely had to play a large part in the damage that ultimately led to my pd. I've had a few people tell me, when I've brought it up, that it only unmasked something that was already there. That may be true, but I would've much preferred had it been unmasked at 80, rather than 25 or so. A big difference, in my opinion. Wendy