Patricia, Leg cramps, particularly in the calves, is common in PD. The probable cause is failure of a muscle to relax pulling in one direction when you are trying to move in the other. The timing is somewhat unusual. Leg cramps for most with PD comes in the early morning. I find that holding my leg fully extended [NO bend in the knees] and relaxing helps. Another solution is a gin & tonic, but hold the gin.. Tonic water contains quinine which has been a specific for leg cramps for well over a hundred years. Will Johnnston A.P.D.A. DelMarVA Chapter Pres. 4049 Oakland School Road Salisbury MD 21804 USA 410-543-0110 ---------- From: Patricia Hewitt <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Subject: Does anyone have any advice? Date: Sunday, August 23, 1998 10:07 AM Months before I was diagnosed with Parkinsons, I started having bad leg cramps (mostly in calfs). These cramps increase when I walk and decrease when I lay down. I first thought I might have a blockage because my cholesterol was 280. The MRI showed I have two herniated discs, L4 and L5, plus scoliosis with degenerative changes. Now the cramps are back. When I walk, my right leg swells. When I lay down, it goes down again. This is very painfull. I take Sinemet 50/200 four times a day and Prozac. When I first started having the cramps, I had not yet been diagnosed with PD and was not taking Sinemet. The neurosurgeon says surgery, a chiropracter says adjustments, my neurologist says PD. Does anyone have any advice? Any input would be appreciated. Thanking you in advance, Patricia Hewitt