Ernie, don't to be quick to come off the Requip. I have had the rash for 6 months now. It started shortly after my late neuro ratcheted my Permax dose way up ( forgot what the dosage was but it was about double what i had been on for the previous 6 months.). When he switched me Mirapex about a month later it abated by about 60% or so but i still have it. It sounds a bit different than yours - mine is mostly confined to my shins with a little on one upper arm, but i have never been on Requip. I have been on Sinement for about 3 years. Go figure! [Congrats on getting that cancer on time! There are a lot worse things than PD, like colon cancer for one. Personally i worry about being so occupied with fighting this beast that something else creeps up on me, like cancer or heart disease. I ran 10-25 miles a week for for 25 years, one reason being the heart disease prevalent in the males of my family. I am now down to zero exercise since May.] There have been other discussions about skin problems . We sufferers of it should keep each other informed of changes and what may have caused them. Bruce Anderson (52,4)