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While talking to my mother Joyce (69/1) tonight, she mentioned that she was having trouble speaking. Her voice has been bad for awhile, very slurred and tired sounding -- also extremely weak. Her voice breaks a lot when she talks, as well. When I asked her to describe the problem she said that it was such an effort to speak. Is this something others feel? Is it a terrible effort? (Of course the new drug mix isn't working as well as we had all hoped. She's getting the brain fog from, she thinks, the Permax.) Thanks. Debbie White [log in to unmask]